You’re extremely thirsty all the time.

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Many diabetes symptoms are subtle, and one of the most telltale signs is increased thirst, according to the Mayo Clinic. If you’re always feeling the urge to reach for your water bottle, it’s something you should bring up to your doctor—especially if you also have blurred vision, increased hunger, and fatigue.
Your muscles keep twitching.

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Muscle twitching shouldn’t be taken lightly. Motor neuron disease is a group of diseases that affect the nerves, causing muscle weakness and stiffness that can mess with your ability to talk, eat, and more, according to the MND Association. As the muscles weaken, uncontrollable twitching can occur.
Or you’re experiencing muscle aches for no reason.

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You didn’t work out recently, so what’s up with your muscle aches? Well, if you’re often out hiking, camping, or spending time in nature, it could be a tick-borne disease. According to the Centers for Disease Control and Prevention (CDC), being bitten by an infected tick could cause you to come down with Lyme disease—some of the most common symptoms of which are muscle aches, fatigue, headache, fever/chills, and a circular rash.
You have constipation or diarrhea.
Experiencing issues like constipation or diarrhea, abdominal pain, feeling super full after eating, and flatulence might seem like issues you can dismiss. But according to the Canadian Society of Intestinal Research, those symptoms are also signs of ovarian cancer. That’s why heading to the doctor to get checked out when those issues can’t be explained by a big meal or a food allergy is so important.
You’re often irritable and angry.

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Oftentimes, depression is thought to be a condition characterized by constant sadness and feelings of hopelessness. And while those are indeed signs of the mental illness, there are also lesser-known symptoms to be aware of, including irritability, angry outbursts, frustration, and agitation. According to the Mayo Clinic, when someone is having a depressive episode, the symptoms can occur pretty much all day, every day.
You have a rash on your body.

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Skin rashes—called dermatitis herpetiformis (DH)—can come hand-in-hand with celiac disease, causing you to become itchy and even blister across your elbows, knees, and rear end, according to Beyond Celiac. One way to tell if your skin flare-ups are due to celiac or not is simple: Does the rash appear after you eat gluten? If so, it could mean you have a sensitivity or intolerance.
You get migraines regularly.

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If you get more migraines than you can count every week, that’s something you can’t keep popping pain meds for—you should discuss it with your doctor. According to a 2016 study published in BMJ, there’s an association between migraines and cardiovascular disease, which can lead to heart attack and stroke.